Twin-roll casting technology is considered the ideal choice for producing magnesium alloy sheets because of itscharacteristics of subrapid solidification, short process flow, and high productivity. However, the inherent center segregationin the sheet material produced by this process poses a significant challenge, as it can negatively impact material propertiesand is difficult to eliminate during subsequent heat treatment processes, thus hindering the development of magnesium alloysheets. Traditional experimental exploration of center segregation mechanisms has proven to be inefficient. With theadvancement of theoretical models and computer technology, numerical calculation and simulation methods have beenwidely adopted to predict center segregation. These methods have demonstrated high accuracy in predicting temperaturefields, concentration fields, and flow fields. This paper reviews the application of solidification models and finite elementsimulations for predicting center segregation, comprehensively analysing the formation mechanisms and various influencingfactors. A critical evaluation of these two methods is provided, along with a prospective outlook on their futuredevelopment in the field of center segregation prediction