Titanium and titanium alloys are widely used in aerospace, machinery manufacturing, biomedical and other fields because of their excellent properties, such as high specific strength, good corrosion resistance and low density. Compared with traditional 316L stainless steel and cobalt-chromium alloys, titanium alloys have relatively lower elastic moduli, excellent corrosion resistance and biocompatibility, gradually attracting the attention of industry personnel. In this work, a Ti-18Zr-13Mo (wt. %) metastable β-Ti alloy was successfully fabricated via laser directed energy deposition based on the mixed element method. The alloy is composed of β phase, with an elastic modulus of 73.5 GPa, a yield strength of 842.2 MPa, and an elongation rate of 20% in the deposition state. The elastic modulus of the alloy can be further reduced to 69.5 GPa by solution treatment. Compared with Ti6Al4V alloys, Ti-18Zr-13Mo alloys can effectively reduce the occurrence of the “stress shielding” phenomenon of implants and can provide sufficient strength support. Therefore, the Ti-18Zr-13Mo alloy is a suitable metastable β biomedical titanium alloy material for bone implants.