Carbon nanotubes (CNTs) reinforced aluminum matrix composites (AMCs) present high specific strength and modulus, excellent corrosion resistance and functional properties such as electrical conductivity and thermal conductivity because they combine the advantages of aluminum matrix and CNTs, showing broad application prospects in the rapidly developing fields of aerospace, rail transit and automotive component lightweighting in recent years. However, there are some bottlenecks in the study of CNTs reinforced AMCs, i.e., CNTs are not easy to disperse uniformly, the wettability between CNTs and aluminum is poor, and Al-CNTs easily react at the interface to form a hard and brittle Al 4 C 3 phase which is easy to hydrolyse. How to solve these problems of the dispersion uniformity of CNTs while inhibiting the interfacial reaction and improving the wettability between Al-CNTs, and promoting the strengthening effect of CNTs in AMCs has become an important research direction in this field. This paper combs and reviews the solutions proposed by researchers for the above problems, summarizes and analyses the effects of various interface regulation strategies on the interface bonding, interface reaction and mechanical properties of AMCs. It lays the experimental and theoretical references for the regulation of the microstructure and performance of CNTs reinforced AMCs based on interface structure design.